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The time period is arbitrary. It relates to the natural rates of conception, i.e. 80% of couples will be pregnant after 12 cycles. Of those who have not conceived after 12 cycles, about 50% will conceive during the second year of attempted conception. After this second year of attempted conception, the chances of conception in those couples remaining are about 50% in the following four years.

Women with primary infertility are twice as likely to obtain treatment as those with secondary infertility.
A male factor is responsible for a couple’s infertility in about 25% of cases. In the last 50 years there has been a documented fall in sperm concentration.

About half of couples with infertility eventually conceive.

Young age, a relatively short period of infertility, and the absence of factors such as bilateral tubal obstruction, azoospermia and prolonged amenorrhoea increase the chances of success.

Three per cent of couples with unexplained infertility conceive each month independently of treatment.

Investigations may include:

* History and examination of both partners
* Semen analysis
* Assessment of ovulation; other methods include basal body temperature, endometrial biopsy
* Other hormonal tests — LH, FSH, TFT’s, testosterone, DHEA, sex hormone binding globulin, PRL — performed on day 2, 3 or 4 of the cycle
* Assessment of cervical compatibility — post-coital test, mucus invasion test
*Assessment of tubal patency, laparoscopy
*Assessment of pelvic adhesions, endometriosis - laparoscopy
* Rubella status — this should be checked prior to the commencement of any treatment; if a patient is non-immune then they should be vaccinated and advised to avoid pregnancy for 3 months.
* People who are concerned about their fertility should be informed that about 84% of couples in the general population will conceive within one year if they do not use contraception and have regular sexual intercourse. Of those who do not conceive in the first year, about half will do so in the second year.

Many of the causes of infertility are unpreventable. But, sometimes you can take preventive measures to optimize your fertility. Some of these methods for prevention include:

* Quit smoking.
* Avoid exposure to chemicals and environmental toxins.
* Limit sexual partners and practise safe sex to avoid STDs.
* Keep your body weight in check, manage your weight if you are obese or severely underweight.
* Keep in shape.
* Get treatment for any conditions that may affect fertility such as diabetes, endometriosis, asthma, and polycystic ovarian syndrome.
* Avoid the use of all illegal substances/drugs

You can increase your ability to conceive by having sex during the fertile time in your cycle, ovulation, by not using protection, and by keeping in top shape during conception, including exercise and healthy nutrition. This goes for both you and your partner.

Treatment

Artificial insemination, also known as intrauterine insemination, is the process of injecting a woman with carefully prepared sperm from her partner, or sperm from a donor. Artificial insemination is used in cases of unexplained infertility, or when a male has minimal amounts of sperm present in his semen, or has other sperm difficulties such as motility issues, or genetic problems. Artificial insemination is used in conjunction with ovulation drugs to optimize the chance for fertilization. It should only be recommended after full tests have been performed on the woman to check for any structural problems, infection or hormonal imbalances that may affect fertilization and pregnancy.

Insemination involves monitoring ovulation through a test kit, ultrasound, or blood tests, to identify the best time to inject the ovulation drugs. The sperm may be applied directly into the uterus or to the cervical opening and released with a catheter passed through a speculum at ovulation. The procedure involved in insemination is relatively quick and painless. It is performed in the doctor’s office, without anaesthesia, and you are free to leave after it is performed.

If the insemination involves donor sperm, the sample is tested for any diseases and prepared at the sperm bank before it is sent to the doctor’s office for insemination. You should be aware that often couples who decide on donor insemination have conflicting emotions about issues such as choosing a donor and whether to tell the child conceived by the insemination.